Obagi360® Retinol 0.5
Obagi360 Retinol Cream by HOO Dermatology
Obagi360 Retinol Cream Texture by HOO Dermatology
Obagi360 Retinol Cream Before and After by HOO Dermatology

Obagi360® Retinol 0.5

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Achieve more with less effort using Obagi® Retinol 0.5. This powerful Retinol cream is designed to revitalize your skin, reducing the look of fine lines and wrinkles while promoting skin renewal with minimal irritation. Our innovative airless pump ensures easy dispensing while safeguarding the formula's integrity and effectiveness.

Skin Type


  • Tolerability is favorable

    • Non-acnegenic

    • Dermatologist tested

    • Minimal to no skin redness, dryness, flaking and irritation, even with stronger Obagi Retinol 1.0 formulation4,†

      4. Final report: A facial irritation evaluation of a cosmetic retinol product after 3 weeks of product use. 1.0% Retinol Cream Formula Number 006-40-11 (GS BK-12-0130F). April 22, 2013. OMP, Inc. Data on file. †Based on a 3-week facial irritation study; N=33.


  • Uncap the airless pump and apply 1 pump, or a pearl-sized amount to your face. Massage until fully absorbed.
  • Use at night.

Key Ingredients


Retinol is a type of retinoid, which is a class of Vitamin A compounds and derivatives that are popular in products designed to improve skin complexion and texture.

Retinol is a non-prescription retinoid that has been shown to reduce the appearance of fine lines and wrinkles, smooth skin texture, and improve overall skin tone.

All ingredients:
water (aqua), caprylic/capric triglyceride, glyceryl stearate, cyclopentasiloxane, butylene glycol, stearic acid, polysorbate 60, butyrospermum parkii (shea) butter, glycerin, stearyl alcohol, cyclohexasiloxane, dimethicone, retinol, calendula officinalis flower extract, camellia sinensis leaf extract, chamomilla recutita (matricaria) flower extract, dipotassium glycyrrhizate, sodium hyaluronate, tocopheryl acetate, bisabolol, ascorbic acid, carthamus tinctorius (safflower) seed oil, sorbitol, glyceryl acrylate/acrylic acid copolymer, dimethicone/vinyl dimethicone crosspolymer, allyl methacrylates crosspolymer, caprylyl glycol, ethylhexylglycerin, hexylene glycol, polysorbate 20, carbomer, disodium EDTA, triethanolamine, BHT, phenoxyethanol

Safety Information

When applying this product, you might notice slight redness, peeling, or skin irritation. These are typical, short-term signs that the product is functioning. If irritation develops, reduce usage to alternate nights or as tolerated. Once your skin has adapted, resume daily use. It's strongly advised to apply a broad spectrum sunscreen with an SPF of 30 or higher every day. Avoid contact with eyes. If contact happens, rinse thoroughly with water. For external use only. Keep away from children's reach.


1. Is Obagi360 Retinol safe for pregnant or nursing moms?
If you are pregnant or suspect that you are pregnant, please do not use Obagi360 Retinol. It is highly recommended to check with your physician regarding any topical products you wish to use during pregnancy or while you are nursing.

2. When can I expect to see results?
You can expect to see results within 4 to 6 weeks, though this may vary per individual.

3. Which product would work best for my skin?
It is best to consult our board-certified dermatologist. He or she will be able to assess which product/s would be suitable for your specific skin type.